Neuroleptics from the 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyridoindole Series. 3. Carboxamidoalkyl Derivatives

Article abstract of DOI:10.1021/jm00160a053

Substitution of position 2 of the 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole nucleus with ω-carboxamidoalkyl substituents leads to compounds with exceedingly potent neuroleptic activity in in vitro and in vivo models.Although duration of a