A stereoselective synthesis of 1-phenyl-1-buten-3-yne and some 1-heteroaryl analogues

Article abstract of DOI:10.1016/S0040-4039(00)74696-X

Z-Enynes, RCH=CHC≡CH (R= phenyl, 2-furyl, 2- and 3-thienyl and 3-pyridyl) can be obtained in ～ 40% overall yields and with a stereoselectivity of> 95% by Pd/Cu-catalyzed cross-coupling of the readily available enyne sulfide HC≡CCH=CHSC₂H_5<