Molecular design and chemical synthesis of potent enediynes. 1. Dynemicin model systems equipped with N-tethered triggering devices

Article abstract of DOI:10.1021/ja00049a022

In this article the molecular design and chemical synthesis of a series of enediynes (12-19, Chart I) related to the dynemicin A structure and carrying N-tethered triggering devices are described. The design envisioned the [(arylsulfonyl)ethoxy]carbonyl g