Synthetic Communications p. 651 - 657 (2002)
Update date:2022-08-04
Topics:
Vasanthakumar, Ganga-Ramu
Suresh Babu, Vommina V.
A simple method for the synthesis of Z-/Boc-/Fmoc-protected β-amino acids by the Arndt-Eistert approach employing p-toluenesulphonyl chloride for the activation of the carboxyl group of Nα-protected amino acid is described. The method is rapid and gave good yields with opitical purity.
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Doi:10.1039/c39920001256
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