Polyazapolycyclics by Condensation of Aldehydes with Amines. 3. Formation of 2,4,6,8-Tetrabenzyl-2,4,6,8-tetraazabicyclooctanes from Formaldehyde, Glyoxal, and Benzylamines

DOI: 10.1021/jo00051a016

Source and publish data:

Journal of Organic Chemistry p. 6756 - 6759 (1992)

Update date:2022-08-05

Topics:

Authors:

Nielsen, Arnold T.

Nissan, Robin A.

Chafin, Andrew P.

Gilardi, Richard D.

George, Clifford F.

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Article abstract of DOI:10.1021/jo00051a016

The condensation of formaldehyde, glyoxal, and benzylamine, in a stoichiometric ratio, leads to 2,4,6,8-tetrabenzyl-2,4,6,8-tetraazabicyclo<3.3.0>octane (1d) in methanol solvent with formic acid catalyst.Six phenyl-sbstituted derivatives of 1d, as well as

Full text of DOI:10.1021/jo00051a016

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