1-Substituted 2-benzylaminobenzimidazole derivatives: Compounds with H1-antihistamine activity

DOI: 10.1016/0223-5234(92)90153-R

Source and publish data:

European Journal of Medicinal Chemistry p. 395 - 400 (1992)

Update date:2022-07-31

Topics:

Authors:

Da Settimo

Primofiore

Da Settimo

Calzolari

Cazzulani

Passoni Passoni

Tofanetti

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(92)90153-R

The preparation of 1-substituted 2-benzylaminobenzimidazole derivatives 13-24 is described. Although these compounds have a different structure from the general structure I of antihistamines, they showed some antihistaminic activity (pA₂: 5-7)

Full text of DOI:10.1016/0223-5234(92)90153-R

Products guided by the article

Product name:[1-Benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-[1-(4-fluoro-benzyl)-1H-benzoimidazol-2-yl]-amine

Cas No:144836-28-2

R&D Labs maybe for 144836-28-2

SHANXI JINJIN CHEMICAL INDUSTRIAL CO.,LTD

website:http://www.jinjingroup.com

Contact:86-574-13989382828

Address:Economic And Technological Development Zone,Hejin?City,Shanxi Province?,China
GUANGZHOU MEDCAN PHARMATECH LTD

website:http://www.gzmedcan.com

Contact:+86-20-82519649

Address:Building J,Room 101,1 JiangtashanRd,Guang Zhou Science City,Guang Zhou ,China
Jiaxing Carry Bio-Chem Technology Co.,Ltd

website:http://www.carrybiotech.com

Contact:0573-82788958

Address:Add.Fl 3th, Pharm Vally,Kaichuang Rd, Xiuzhou District, Jiaxing, Zhejiang,314031,China
Sino-Japan Chemical Co., Ltd.

website:http://www.sjc.com.tw

Contact:(886) 2-2396-6223

Address:14Fl., No. 99. Sec. 2, Jen Ai Road
Nanjing Fred Technology Co.,Ltd.

website:http://www.fredbio.com

Contact:+86-25-84696168

Address:Nanjing

Relevant to this article

A new fluorescent and colorimetric probe for trace hydrazine with a wide detection range in aqueous solution

Doi:10.1016/j.dyepig.2013.08.008
(2013)
Direct C-H sulfenylation of purines and deazapurines

Doi:10.1039/c3ob40881g
(2013)
SYNTHESIS AND INVESTIGATION OF THE MESOMORPHIC PROPERTIES OF PYRAN DERIVATIVES

Doi:10.1007/BF00529366
(1992)
Microsolvation and ¹³C-Li NMR coupling

Doi:10.1021/ja8026828
(2008)
N-heterocyclic carbene-phosphinidyne transition metal complexes

Doi:10.1002/anie.201408354
(2014)
A photochemical route to benzo[a]carbazoles via domino elimination/ electrocyclization of 2-aryl-3-(1-tosylalkyl)indoles

Doi:10.1002/adsc.201201051
(2013)

Article Doi