1-Substituted 2-benzylaminobenzimidazole derivatives: Compounds with H1-antihistamine activity

DOI: 10.1016/0223-5234(92)90153-R

Source and publish data:

European Journal of Medicinal Chemistry p. 395 - 400 (1992)

Update date:2022-07-31

Topics:

Authors:

Da Settimo

Primofiore

Da Settimo

Calzolari

Cazzulani

Passoni Passoni

Tofanetti

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(92)90153-R

The preparation of 1-substituted 2-benzylaminobenzimidazole derivatives 13-24 is described. Although these compounds have a different structure from the general structure I of antihistamines, they showed some antihistaminic activity (pA₂: 5-7)

Full text of DOI:10.1016/0223-5234(92)90153-R

Products guided by the article

Product name:[1-Benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-[1-(4-fluoro-benzyl)-1H-benzoimidazol-2-yl]-amine

Cas No:144836-28-2

R&D Labs maybe for 144836-28-2

Weihao Chemtech (ChangZhou) Co., Ltd.(expird)

Contact:051989185693

Address:NO 217 huangshan Rd ,Changzhou
henan victory industry co.ltd

Contact:86-371-63655023

Address:No.85,jinshui road,zhengzhou,China
KINHENG CHEMICAL(SHANGHAI)CO., LTD.

Contact:+8621-60490170

Address:Room401, No.28,Lane 189, Yangshupu Rd. Shanghai, China.
Shanghai AoBo Bio-Pharmaceutical Technology Co., Ltd.

Contact:+86-21-51320130-801, 816

Address:Room 601, No. 1011, Halei Road, Zhangjiang High-Tech Park, Pudong, Shanghai
Hangzhou Eastbiopharm Co.,Ltd.

Contact:+86-571-88931780

Address:Hangzhou,China

Relevant to this article

A new fluorescent and colorimetric probe for trace hydrazine with a wide detection range in aqueous solution

Doi:10.1016/j.dyepig.2013.08.008
(2013)
Direct C-H sulfenylation of purines and deazapurines

Doi:10.1039/c3ob40881g
(2013)
SYNTHESIS AND INVESTIGATION OF THE MESOMORPHIC PROPERTIES OF PYRAN DERIVATIVES

Doi:10.1007/BF00529366
(1992)
Microsolvation and ¹³C-Li NMR coupling

Doi:10.1021/ja8026828
(2008)
N-heterocyclic carbene-phosphinidyne transition metal complexes

Doi:10.1002/anie.201408354
(2014)
A photochemical route to benzo[a]carbazoles via domino elimination/ electrocyclization of 2-aryl-3-(1-tosylalkyl)indoles

Doi:10.1002/adsc.201201051
(2013)

Article Doi