Synthesis of 3'-alkylthio-2',3'-dideoxy nucleosides with potential anti-HIV activity from 2-deoxy-D-ribose, using a phosphorus pentoxide reagent

DOI: 10.1002/ardp.19923250914

Source and publish data:

Archiv der Pharmazie p. 597 - 601 (1992)

Update date:2022-08-04

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Authors:

Dueholm Dueholm

Motawia Motawia

Pedersen

Nielsen Nielsen

Lundt Lundt

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Article abstract of DOI:10.1002/ardp.19923250914

Direct condensation of 2-deoxy-D-ribose (1) with mercaptans using the P₄O₁₀/H₂O/Bu₃N reagent in chloroform resulted in coupling at C-3 to give the anomeric mixtures of the corresponding pentopyranoses 2 and pent

Full text of DOI:10.1002/ardp.19923250914

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