Enzyme-catalysed Hydrolysis of Dimethyl 7-Hydroxy-3,3-dimethyl-2,4-dioxabicyclooctane-6,8-dicarboxylate and a Novel Synthesis of Neplanocin A

DOI: 10.1039/P19920002245

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2245 - 2246 (1992)

Update date:2022-08-04

Topics:

Authors:

Hutchinson, Edward J.

Roberts, Stanley M.

Thorpe, Andrew J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/P19920002245

Hydrolysis of the diester 1 catalysed by pig liver esterase provided the mono-ester 3.This ester was converted into the amine 9, a precursor of neplanocin 10, thereby confirming the previously proposed configuration of 3.

Full text of DOI:10.1039/P19920002245

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:methyl(3R,4S,5R)-4,5-isopropylidenedioxy-3-<(triphenylmethyl)amino>cyclopent-1-enecarboxylate

Cas No:144874-43-1

R&D Labs maybe for 144874-43-1

Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Luzhou North Chemical Co., Ltd.

Contact:+86-830-2796784；+86-830-2796776

Address:Gaoba, Longmatan District, Luzhou, Sichuan Province
Shanghai united Scientific Co.,Ltd.

Contact:+86-21-53535353

Address:28F No.900 huaihai Road Shanghai China
Hisyntech Corporation Limited

Contact:0086-22-23410962

Address:17-201, Ningfuli, Shuishanggongyuandong road,Nankai district, Tianjin, China
Hangzhou Bayee Chemical Co.,Ltd.

Contact:+86-571-86990109

Address:No.380, Jiangnan Auenue, Binjiang District, Hangzhou, China

Relevant to this article

Mo(VI)-catalyzed synthesis of 2-aryl-2H-indazoles using pinacol mediated deoxygenation of nitroaromatics

Doi:10.1246/cl.190490
(2019)
Synthesis of amphotericin B. I. Fragment A of the aglycon

Doi:10.1021/jo00189a046
(1984)
Microwave assisted efficient aminocarbonylation of N-tosylhydrazones with molybdenum hexacarbonyl and amines

Doi:10.1016/j.tetlet.2013.07.149
(2013)
Total synthesis of emericellamides A and B

Doi:10.1016/j.tetasy.2013.07.012
(2013)
Highly stereoselective transformation of (1S,3S)-cis-1,3-disubstituted tetrahydro-β-carbolines into (1S,3R)-trans-1,3-disubstituted tetrahydro-β-carbolines: An improved asymmetric synthesis of tadalafil from l-tryptophan

Doi:10.1016/j.tetasy.2013.06.006
(2013)
Chiral bifunctional squaramide catalyzed asymmetric tandem Michael-cyclization reaction: Efficient synthesis of optically active 2-amino-4H-chromene-3-carbonitrile derivatives

Doi:10.1016/j.tetasy.2013.07.010
(2013)

Article Doi