Molecular design, chemical synthesis, and study of novel enediyne-sulfide systems related to the neocarzinostatin chromophore

DOI: 10.1021/ja00122a012

Source and publish data:

Journal of the American Chemical Society p. 4822 - 4831 (1995)

Update date:2022-08-03

Topics:

Authors:

Toshima, Kazunobu

Ohta, Kazumi

Ohashi, Aya

Nakamura, Takatsugu

Nakata, Masaya

Tatsuta, Kuniaki

Matsumura, Shuichi

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Article abstract of DOI:10.1021/ja00122a012

The design and synthesis of the novel monocyclic enediyne-sulfide systems and their chemical and DNA cleavage properties are described. The parent enediyne-sulfide 6 possessing a hydroxy group at the allylic position was effectively synthesized via the cr

Full text of DOI:10.1021/ja00122a012

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