Preparation of optically active succinic acid derivatives: I. Optical resolution of 2-benzyl-3-(cis-hexahydroisoindolin-2-ylcarbonyl)-propionic acid

DOI: 10.1248/cpb.45.1518

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1518 - 1520 (1997)

Update date:2022-08-04

Topics:

Authors:

Yamaguchi, Toshiaki

Yanagi, Takashi

Hokari, Hiroshi

Mukaiyama, Yuko

Kamijo, Tetsuhide

Yamamoto, Iwao

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.45.1518

(+)-Monocalcium bis[(2S)-2-benzyl-3-(cis-hexahydroisoindolin-2- ylcarbonyl)propionate] dihydrate (KAD-1229, 1) is an optically active succinic acid calcium salt derivative with potent hypoglycemic effect. We investigated two optical resolution method. 2-B

Full text of DOI:10.1248/cpb.45.1518

NII-Electronic Library Service

Products guided by the article

Product name:4-(3aR,7aS)-Octahydro-isoindol-2-yl-4-oxo-2-[1-phenyl-meth-(E)-ylidene]-butyric acid

Cas No:145323-82-6

R&D Labs maybe for 145323-82-6

A.M FOOD CHEMICAL CO., LIMITED

Contact:86-531-87100375

Address:20Floor，Bblock，1Building，pharma-valley，Jinan，China
Joyochem Co., Ltd.

website:https://sdjingyuan.lookchem.com/

Contact:86-531-82687998

Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China
Mollt Biochem Co., Ltd(expird)

Contact:+86-21-38682181

Address:shanghai ,china
DU-HOPE INTERNATIONAL GROUP

Contact:+86-25-52346955

Address:199,JIANYE ROAD,NANJING,CHINA
Shanghai Zhihua ChemTech Co., Ltd.

Contact:+86-13774313779

Address:Room 817 Suite B 3333 Shenjiang Road

Relevant to this article

Synthesis and characterization of all possible diastereoisomers of alvimopan

Doi:10.13005/ojc/340246
(2018)
Sodium p-toluenesulfinate/copper(II) acetate in free radical reactions

Doi:10.1016/S0040-4039(00)60961-9
(1992)
Green synthesis of 1-(1,2,4-Triazol-4-yl)spiro[azetidine-2,3′-(3 H)indole]-2′,4′(1′ H)-diones as potential insecticidal agents

Doi:10.1002/jhet.1071
(2013)
Highly Enantioselective Reduction of 3-Chloro-2-oxoalkanoates with Fermenting Bakers' Yeast. A New Synthesis of Optically Active 3-Chloro-2-hydroxyalkanoates and Glycidic Esters

Doi:10.1021/jo00054a036
(1993)
Asymmetric syntheses of dihydroxyhomoprolines via doubly diastereoselective lithium amide conjugate addition reactions

Doi:10.1016/j.tet.2013.07.096
(2013)
The Stevens <1,2>-Shift of Oxonium Ylides: A Route to Substituted Tetrahydrofuranones

Doi:10.1021/jo00038a043
(1992)

Article Doi