Cyclic peptides as selective tachykinin antagonists

DOI: 10.1021/jm00053a001

Source and publish data:

Journal of Medicinal Chemistry p. 2 - 10 (1993)

Update date:2022-08-02

Topics:

Authors:

Williams

Curtis Curtis

McKnight

Maguire Maguire

Young Young

Veber Veber

Baker Baker

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Article abstract of DOI:10.1021/jm00053a001

Twenty homodetic cyclic peptides based on the C-terminal sequence of substance P were prepared (Table I) by a combination of solid-phase techniques and cyclizations using azide coupling procedures. Incorporation of dipeptide mimics based on substituted γ-

Full text of DOI:10.1021/jm00053a001

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