Total synthesis of chelerythrine, a benzo[c]phenanthridine alkaloid

DOI: 10.1248/cpb.40.2002

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2002 - 2006 (1992)

Update date:2022-09-26

Topics:

Authors:

Ishii Ishii

Ishikawa

Takeda Takeda

Suzuki Suzuki

Harayaya

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.2002

By taking advantage of our novel synthetic methods involving CsF-mediated Claisen rearrangement of an aryl propargyl ether to a 2-methylbenzolfuran and oxidative cleavage of the furan ring to a salicylaldehyde, total synthesis of chelerythrine, a benzo[c]phenanthridine alkaloid, was accomplished via the common intermediate (5) prepared through the two routes shown in Chart 3.

Full text of DOI:10.1248/cpb.40.2002

NII-Electronic Library Service

Products guided by the article

Product name:2-(2-formyl-3,4-dimethoxyphenyl)-1-(N-methylformamido)-6,7-methylenedioxynaphthalene

Cas No:145654-10-0

R&D Labs maybe for 145654-10-0

SHANDONG CREDAGRI CHEMICAL CO., LTD.

Contact:+86-531-88872050

Address:ROOM 601A, BUILDING 2, SHUNTAI SQUARE, NO. 2000 SHUNHUA ROAD, HI-TECH DEVELOPMENT ZONE, JINAN, CHINA.
Zhuhai Rundu Pharmaceutical co.,Ltd

Contact:+86-756-7630755

Address:No.6,North Airport Road,Sanzao Town,Jinwan District
JIAXING SUNS INTERNATIONAL TRADE CO LTD

Contact:18367306858

Address:No.123,Huixin Avenue,Huimin Dist
Zibo Kunran Enterprises Co. LTD

website:http://www.kunranchem.com

Contact:0086 533 5200669

Address:No. 96 Jinjing Avenue, Zibo, Shandong, China
Synasia Inc

Contact:17316303296

Address:240 Amboy Ave

Relevant to this article

Doi:10.1021/jo01288a002
(1967)
Convenient method for the preparation of aryl sulfinyl chlorides

Doi:10.1055/s-2001-17437
(2001)
Modular synthesis of the C9-C27 degradation product of aflastatin a via alkyne-epoxide cross-couplings

Doi:10.1021/ol800659z
(2008)
Synthesis and in vitro anti-proliferative activity of β-elemene monosubstituted derivatives in HeLa cells mediated through arrest of cell cycle at the G1 phase

Doi:10.1016/j.bmc.2008.12.040
(2009)
A new type of NADH model compound: Synthesis and enantioselective reduction of benzoylformates to the corresponding mandelates

Doi:10.3390/12050979
(2007)
Titanium-mediated fragment union processes in complex molecule synthesis: Development of a branched reaction pathway of high step economy for the synthesis of complex and diverse polyketides

Doi:10.1055/s-2008-1032160
(2008)

Article Doi