Evaluation of Mannich bases and related compounds as inhibitors of mitochondrial function in yeast and inhibition of blood platelet aggregation, blood clotting, and in vitro metabolism of 5 dimethylamino 1 phenyl 1 penten 3 one hydrochloride

Article abstract of DOI:10.1002/jps.2600650403

5 Dimethylamino 1 phenyl 1 penten 3 one hydrochloride (Ia) and 32 analogs were tested for inhibition of respiratory dependent growth in Saccharomyces cerevisiae. 13 Of the 33 compounds tested appeared to affect mitochondrial function, since the inhibition