New Hybrid Transition State Analog Inhibitors of HIV Protease with Peripheric C2-Symmetry

DOI: 10.1016/S0040-4039(00)61002-X

Source and publish data:

Tetrahedron Letters p. 6625 - 6628 (1992)

Update date:2022-07-31

Topics:

Authors:

Stowasser, Bernd

Budt, Karl-Heinz

Jian-Qi, Li

Peyman, Anusch

Ruppert, Dieter

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)61002-X

The synthesis of novel hybrid transition state analogs, a combination of phosphinic acid- and hydroxymethylene-type inhibitors of HIV protease, is demonstrated.These nonsymmetrical structures, placed in a peripheric C₂-symmetrical environment,

Full text of DOI:10.1016/S0040-4039(00)61002-X

Products guided by the article

Product name:(2-Benzyloxycarbonylamino-1-hydroxy-3-phenyl-propyl)-((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-phosphinic acid ethyl ester

Cas No:146063-28-7

R&D Labs maybe for 146063-28-7

SHUNYUANSHENG BIO-PHARMTECH CO., LTD

website:https://www.whsysbio.com

Contact:--

Address:Building 13, Liandong U Valley-Wuhan Economic Innovation Valley, No. 259, Xingsan Road, Shamao Street, Hannan District, Wuhan City, Hubei Province
Evergreen Chemical Industry Ltd.

Contact:86-553-4918210

Address:6#2-602 Wanhaobailing
Goldwills Pharmaceuticals Co., Ltd.

Contact:0916-2237889 13991621155

Address:North Suburb of Hanzhong city, Shaanxi Province
Tianjin Boron PharmaTech Co.,Ltd.(expird)

Contact:86-022-59845187

Address:B9-401, Tianda Science Park,No.80,4th Avenue,TEDA,Tianjin, China
Suzhou JMS Chemical Co., Ltd.

Contact:+86-15995924277

Address:WuZhongOu suzhou new south road 89

Relevant to this article

Base-catalysed Ring Contraction of 6,7-Dihydro-1-methyl-1H-1,2,5-triazepines to 2,3-Dimethyl-1,2,4-triazines

Doi:10.1039/P19920003233
(1992)
The solvent-free synthesis of polysubstituted pyrroles by a reusable copper Schiff base complex immobilized on silica coated Fe₃O₄, and DNA binding study of one resulting derivative as a potential anticancer drug

Doi:10.1002/aoc.4754
(2019)
Thermal ene reactions of alloxan and 1,3-dimethylalloxan

Doi:10.1016/S0040-4020(01)80521-4
(1993)
Synthesis of axially dissymmetric biphenylbisphosphine ligands, BIMOPs and asymmetric hydrogenations of β-keto ester and α,β-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes

Doi:10.1248/cpb.39.1085
(1991)
Synthesis of novel optically active poly(phenyleneethynylene- aryleneethynylene)s bearing hydroxy groups. Examination of the chiroptical properties and conjugation length

Doi:10.1021/ma401730e
(2013)
Novel morpholine scaffolds as selective dopamine (DA) D3 receptor antagonists

Doi:10.1016/j.bmcl.2015.12.081
(2016)

Article Doi