New Hybrid Transition State Analog Inhibitors of HIV Protease with Peripheric C2-Symmetry

DOI: 10.1016/S0040-4039(00)61002-X

Source and publish data:

Tetrahedron Letters p. 6625 - 6628 (1992)

Update date:2022-07-31

Topics:

Authors:

Stowasser, Bernd

Budt, Karl-Heinz

Jian-Qi, Li

Peyman, Anusch

Ruppert, Dieter

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Article abstract of DOI:10.1016/S0040-4039(00)61002-X

The synthesis of novel hybrid transition state analogs, a combination of phosphinic acid- and hydroxymethylene-type inhibitors of HIV protease, is demonstrated.These nonsymmetrical structures, placed in a peripheric C₂-symmetrical environment,

Full text of DOI:10.1016/S0040-4039(00)61002-X

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