New Hybrid Transition State Analog Inhibitors of HIV Protease with Peripheric C2-Symmetry

DOI: 10.1016/S0040-4039(00)61002-X

Source and publish data:

Tetrahedron Letters p. 6625 - 6628 (1992)

Update date:2022-07-31

Topics:

Authors:

Stowasser, Bernd

Budt, Karl-Heinz

Jian-Qi, Li

Peyman, Anusch

Ruppert, Dieter

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)61002-X

The synthesis of novel hybrid transition state analogs, a combination of phosphinic acid- and hydroxymethylene-type inhibitors of HIV protease, is demonstrated.These nonsymmetrical structures, placed in a peripheric C₂-symmetrical environment,

Full text of DOI:10.1016/S0040-4039(00)61002-X

Products guided by the article

Product name:(2-Benzyloxycarbonylamino-1-hydroxy-3-phenyl-propyl)-((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-phosphinic acid ethyl ester

Cas No:146063-28-7

R&D Labs maybe for 146063-28-7

JIN TAN CHENG'EN CHEMICAL CO.,LTD.

Contact:86-519-82116250

Address:NO.102，village Dongfang，conomic development zone
Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China
Jitat Company Ltd

Contact:852-27701081

Address:Room 2509, New Tech Plaza, 34 Tai Yau St., San Po Kong, HK
Dalian Synco Chemical Co., Ltd.

Contact:+86-411-83635150

Address:Rm 1004, 24, Tangshan Street, Dalian
JADECHEM NINGBO CO.,LTD.

Contact:+86-574-89075960

Address:#100 Xiang Yun Road, New High tech area, Ningbo, China

Relevant to this article

Base-catalysed Ring Contraction of 6,7-Dihydro-1-methyl-1H-1,2,5-triazepines to 2,3-Dimethyl-1,2,4-triazines

Doi:10.1039/P19920003233
(1992)
The solvent-free synthesis of polysubstituted pyrroles by a reusable copper Schiff base complex immobilized on silica coated Fe₃O₄, and DNA binding study of one resulting derivative as a potential anticancer drug

Doi:10.1002/aoc.4754
(2019)
Thermal ene reactions of alloxan and 1,3-dimethylalloxan

Doi:10.1016/S0040-4020(01)80521-4
(1993)
Synthesis of axially dissymmetric biphenylbisphosphine ligands, BIMOPs and asymmetric hydrogenations of β-keto ester and α,β-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes

Doi:10.1248/cpb.39.1085
(1991)
Synthesis of novel optically active poly(phenyleneethynylene- aryleneethynylene)s bearing hydroxy groups. Examination of the chiroptical properties and conjugation length

Doi:10.1021/ma401730e
(2013)
Novel morpholine scaffolds as selective dopamine (DA) D3 receptor antagonists

Doi:10.1016/j.bmcl.2015.12.081
(2016)

Article Doi