
Journal of Medicinal Chemistry p. 919 - 923 (1993)
Update date:2022-08-04
Topics:
Vrudhula, Vivekananda M.
Senter, Peter D.
Fischer, Keith J.
Wallace, Philip M.
The syntheses and cytotoxic activities of substituted N-phenylacetamido derivatives of doxorubicin and melphalan are described.The derivatives were designed as prodrugs which could be activated in a site-specific manner by monoclonal antibody-penicillin-G
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