A Total Synthesis of 6,7-Dihydroeponemycin and Determination of Stereochemistry of the Epoxide Ring

DOI: 10.1016/S0040-4039(00)77488-0

Source and publish data:

Tetrahedron Letters p. 1047 - 1050 (1993)

Update date:2022-08-04

Topics:

Authors:

Hoshi, Hideaki

Ohnuma, Takeshi

Aburaki, Shimpei

Konishi, Masataka

Oki, Toshikazu

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Article abstract of DOI:10.1016/S0040-4039(00)77488-0

A total synthesis of 6,7-dihydroeponemycin 2 was achieved via the epoxide intermediate 8a.Unresolved absolute configuration of the epoxide ring in 2 and eponemycin 1 was determined to be 2R by application of the asymmetric Sharpless epoxidation of 9.

Full text of DOI:10.1016/S0040-4039(00)77488-0

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