Optically active oxazolidinones as Michael donors for the short and efficient synthesis of β-amino acids containing a cyclopropane ring

Article abstract of DOI:10.1016/S0040-4039(00)60569-5

The Michael addition of optically active 3,4-diphenyloxazolidinone 5 to 2′-substituted 2-chloro-2-cyclopropylideneacetates yields 2′-substituted 2-cyclopropyl-1′-(2-oxo-3,4-diphenyloxazolidin-3-yl)acetates 6-R with excellent trans-selectivity, which upon