Chemical and Pharmaceutical Bulletin p. 2921 - 2926 (1992)
Update date:2022-07-30
Topics: Synthesis Characterization Scale-up Publication and Patenting Design Motivation Catalytic Evaluation
Inoguchi
Fujie
Yoshikawa
Achiwa
A new chiral 1,3-bisphosphine, (1R,2R)-1-diphenylphosphino-2-(diphenylphosphinomethyl)cyclopentane, which was designed to form the favorable skew conformation of the six-membered chelate with rhodium, was developed. Its rhodium complex was found to be one of the most efficient catalysts known for asymmetric hydrogenation of amino acid precursors. Further improvement of this ligand was also attempted for catalytic asymmetric hydrogenation of prochiral ketones to clarify the enantioselective mechanism.
View MoreQINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.
Contact:+86 532 80861829
Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
AllyChem Co., Ltd., Dalian, China（BBChem）
Contact:+86-411-62313318/62313328
Address:No.5 of Jinbin Road, Jinzhou New District, Dalian City, Liaoning Province, P.R.China
Shijiazhuang Haotian Chemical Co., Ltd.
Contact:86-311-85044374
Address:293 Donggang Road
Contact:021-36356756
Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Contact:+65 9658 0999
Address:26 Sin Ming Lane, Midview City, #05-118, Singapore 573971
Doi:10.1021/ol503491t
(2015)Doi:10.1039/a805548c
(1998)Doi:10.1021/jo981965s
(1999)Doi:10.1007/BF00904331
(1968)Doi:10.1021/ja01536a028
(1958)Doi:10.1016/S0960-894X(98)00700-8
(1999)
