Journal of Organic Chemistry p. 3148 - 3155 (1993)
Update date:2022-08-04
Topics:
Hamdouchi, C.
Topolski, M.
Goedken, V.
Walborsky, H. M.
The synthesis of chiral 1-bromo-1-methylspiro<2.5>octane (13) is described.The absolute configuration of 13 has been established as (S)-(+).From stereochemistry, product analysis, and radical trapping experiments it is concluded that the reaction of chiral 13 with magnesium to form the corresponding Grignard reagent occurs mainly on the surface of the magnesium.
View MoreContact:+86-575-82733999 0575-82732999
Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province
Taizhou Chemedir Biopharm-tech Co., Ltd
Contact:+86 523 86200218
Address:G09, No. 1 Avenue China Medical City, Taizhou,Jiangsu, China
Contact:+ 86 512 52491118
Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Chongqing KonAo Health Co.,Ltd
Contact:13687578375
Address:wuhan hubei china
Taixing Joxin Bio-tec Co.,Ltd.
website:http://www.joxbio.com
Contact:86-523-87558858 87612088
Address:No.88, chengdong industrial park
Doi:10.1002/pola.26811
(2013)Doi:10.1016/S0022-1139(00)80105-0
(1993)Doi:10.1016/j.tetlet.2006.05.107
(2006)Doi:10.1021/jo00113a030
(1995)Doi:10.1002/anie.199304181
(1993)Doi:10.1055/s-1999-2712
(1999)
