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Synthesis of 6&β-methyl analogues of mifepristone, new selective antiprogestagens

DOI: 10.1002/recl.19931120206

Source and publish data:

Recueil des Travaux Chimiques des Pays-Bas p. 107 - 112 (1993)

Update date:2022-08-04

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Authors:

Heuvel, M. J. van denHeuvel, M. J. van den

Groen, M. B.Groen, M. B.

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Article abstract of DOI:10.1002/recl.19931120206

A new strategy is described to synthesize 19-norsteroids with substituents at C-6, C-11 and C-17.The strategy is applied to the synthesis of 11β-<4-(dimethylamino)phenyl>-6β-methyl-4',5'-dihydrospiro-3-one (15, Org 31710

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Full text of DOI:10.1002/recl.19931120206

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Product name:3,3-dimethoxy-11β-<4-(dimethylamino)phenyl>-6β-methyl-17α-(3-tetrahydropyranyloxy-1-propynyl)estr-9-ene-5α,17β-diol

Cas No:148676-90-8

148676-90-8

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