Stereocontrolled synthesis of p-substituted trifluoromethylbenzylic alcohol derivatives of high optical purity by the Baker's yeast reduction

Article abstract of DOI:10.1016/S0957-4166(00)80234-7

The enantioselectivity of the bakers' yeast reduction of p-substituted trifluoroacetylbenzene derivatives could be improved by the introduction of some functional groups at the para-position to give the corresponding (R)-trifluoromethyl-substituted benzyl