One pot synthesis of 2,6-dichloro-3,5-dicyanopyridine from aliphatic precursors

Article abstract of DOI:10.1080/00397919308012595

Malononitrile is condensed with triethyl orthoformate in the presence of pyridine; the mixture is acidified with HCl gas and after addition of further pyridine, HCl diazotised to form 2,6-dichloro-3,5-dicyanopyridine in a convenient, high yield process.

Full text of DOI:10.1080/00397919308012595

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Synthetic Communications: An
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One Pot Synthesis of 2,6-
Dichloro-3,5-dicyanopyridine
from Aliphatic Precursors
Antoine Duindam a , Vadim L. Lishinsky a & Doetze J.
Sikkema a
a Akzo Research Laboratories Arnhem , P O Box
9300, 6800, Arnhem, the Netherlands
Published online: 24 Sep 2006.
To cite this article: Antoine Duindam , Vadim L. Lishinsky & Doetze J. Sikkema (1993)
One Pot Synthesis of 2,6-Dichloro-3,5-dicyanopyridine from Aliphatic Precursors,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 23:18, 2605-2609, DOI: 10.1080/00397919308012595
To link to this article: http://dx.doi.org/10.1080/00397919308012595
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