Heterocycles p. 937 - 940 (1993)
Update date:2022-07-29
Topics:
Matsuki, Kenji
Inoue, Hirozumi
Ishida, Akihiko
Takeda, Mikio
Bicyclic-5-hydroxy-2-pyrrolidinones (2a-f) were synthesized with high enantioselectivity by the reduction of meso-cyclic-1,2-dicarboximides (1a-f) with lithium aluminum hydride (LiAlH4)-methanol(MeOH)-1,1-bi-2-naphthol complex (BINAL-H).Treatment of 2a-f with triethylsilane (Et3SiH) and trifluoroacetic acid (CF3CO2H) gave optically active 2-pyrrolidinones (3a-f) in quantitative yields.For the absolute configuration correlation, 2a-d were converted into known lactones (4a-d).
View MoreJiangsu Institute of Ecomones Co., Ltd
website:http://www.jsmone.com
Contact:+86-519-82821700
Address:95 Huanyuan N. Road, Jintan, Jiangsu, China
LinHai Cina Chemical Co., LTD.
Contact:0576-85580989
Address:Pharma-chem zone,Duqiao,Linhai,Zhejiang,China
Beijing Wisdom Chemicals Co., Ltd.
Contact:+86-10-52350335
Address:F2, BLDG 19, Liando Valley U, Majuqiao, Tongzhou District, Beijing, China
website:https://sdjingyuan.lookchem.com/
Contact:86-531-82687998
Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China
Beijing Tianjia Chemical Science & Technology Co.,Ltd
Contact:86-0550-2392698
Address:No.388, Shiliang Road (East),
Doi:10.1016/S0040-4020(01)97150-9
(1974)Doi:10.1016/S0957-4166(00)80366-3
(1993)Doi:10.1016/j.bmcl.2013.11.034
(2014)Doi:10.1055/s-1999-3684
(1999)Doi:10.1016/0223-5234(93)90123-V
(1993)Doi:10.1021/jo00076a006
(1993)
