Synthesis of C2-Symmetric Compounds via Double Alkylation of (α,ω-Dioxo-alkanediyl)bis-2-oxazolidinone Derivatives

Article abstract of DOI:10.1016/S0040-4020(01)85733-1

A series of chiral C2-symmetric compounds was prepared from readily available α,ω-diacyl chlorides and optically pure 2-oxazolidinone derivatives.Following preparation of the asymmetrically pure bis-oxazolidinone derivatives (6a-d, 11, 13, and 20), we pre