Total Synthesis and Biological Properties of Novel Antineoplastic (Chloromethyl)furanoindolines: An Asymmetric Hydroboration Mediated Synthesis of the Alkylation Subunits

DOI: 10.1021/jm00028a005

Source and publish data:

Journal of Medicinal Chemistry p. 232 - 239 (1994)

Update date:2022-09-26

Topics:

Authors:

Mohamadi, Fariborz

Spees, Michael M.

Staten, Gilbert S.

Marder, Philip

Kipka, Julia K.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00028a005

1,2-Dihydro-1-(chloromethyl)-5-hydroxy-8-methyl-3H-furano<3,2-e>indole (CFI) as a novel replacement of the cyclopropylpyrroloindoline (CPI) alkylation subunit of CC-1065, U-71184, and U-73975 (adozelesin) has been synthesized and incorporated into a serie

Full text of DOI:10.1021/jm00028a005

Products guided by the article

Product name:1-(1-(1-oxa-2-butenyl))-2-methoxy-4-nitrobenzene

Cas No:153001-63-9

R&D Labs maybe for 153001-63-9

Beijing Stable Chemcial Co.ltd

Contact:86-10-63785052

Address:A1301 Technological Edifice. No.4 FuFeng Road,FengTai District, Beijing. China
Angel Yeast Co., Ltd.

Contact:+86-717-6370352

Address:168 Chengdong Avenue, Yichang, Hubei 443003, P. R.China
Suzhou Chiral Pharmaceuticals Co., Ltd.

Contact:86-0512-63197058

Address:Building A, No. 2358, Chang'an Road, Wujiang Science Park
Zhongshan Haihong Medicine Co., Ltd.

Contact:86-0760-86925778 （0）18824993998

Address:A7 building,lianyuan road Torch Hi-tech Industrial Development Zone
Nanjing Fayekong Chemcial Co.,Ltd(expird)

Contact:86-25-58813444

Address:Rm 1503, Unit 1, Building 5, Zijinnanyuan, Nanjing, Jiangsu, China

Relevant to this article

A novel route to a new lactone intermediate for C-nucleosides via an intramolecular sulfonium ylide rearrangement. A formal synthesis of (+)-showdomycin

Doi:10.1016/S0040-4039(00)60417-3
(1993)
8-(1H-imidazol-1-yl)-7-nitro-4(5H)-imidazo[1,2-a]quinoxalinone and related compounds: Synthesis and structure-activity relationships for the AMPA-type non-NMDA receptor

Doi:10.1021/jm960664c
(1997)
Studies on RA derivatives. V. Synthesis and antitumor activity of Ala²- modified RA-VII derivatives

Doi:10.1248/cpb.41.1402
(1993)
Laser-initiated chemical chain reactions

Doi:10.1063/1.439284
(1980)
Bromdisilan: Verbesserte Synthese, Schwingungsspektren und Normalkoordinatenanalyse

Doi:10.1016/0584-8539(94)80121-5
(1994)
INTRAMOLECULAR CYCLIZATION WITH IMINIUM IONS. SYNTHESIS OF 1,4-DIAZABICYCLO<4.3.1>DECENE DERIVATIVES

Doi:10.1016/S0040-4039(00)79346-4
(1993)

Article Doi