Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case

Article abstract of DOI:10.1016/j.tetasy.2009.03.021

Per-O-acetylated β-d-glucopyranosyl azide was transformed into an intermediate iminophosphorane by PMe₃ which was then acylated to N-acyl-β-d-glucopyranosylamines. The same azide and substituted acetylenes gave 1-(β-d-glucopyranosyl)-4-substitu