Chemical and Pharmaceutical Bulletin p. 1412 - 1414 (1996)
Update date:2022-09-26
Topics:
Satoh, Masato
Okamoto, Yoshinori
Koshio, Hiroyuki
Ohta, Mitsuaki
Nishida, Akito
Akuzawa, Shinobu
Miyata, Keiji
Mase, Toshiyasu
Semple, Graeme
A series of (3-substituted phenyl)urea analogues of the potent gastrin/cholecystokinin (CCK)-B receptor antagonist YM022 has been prepared. Structure activity relationship studies of this series suggested that a number of analogues retained good in vitro potency for gastrin/CCK-B receptor. In particular, the (3-amino substituted phenyl)urea derivatives (10-12) were more potent inhibitors of pentagastrin-induced gastric acid secretion in rats than YM022 on intraduodenal (i.d.) administration.
View Morewebsite:https://www.sinoshiny.com/products
Contact:+86-20-62802632;62802633
Address:Room 330 GIGCAS Building,No.511 Kehua Street,Tianhe District
Shanghai Goyic Pharmaceutical&Chemical Co,. Ltd
Contact:+86-021-60275964
Address:No. 528 ruiqing road
Yangling Ciyuan biotech Co., Ltd.
Contact:86-15802970736
Address:2-1804, International Park Mansion, No.2, South Fengdeng Road, Lianhu District
Hangzhou J&H Chemical Co., Ltd.
website:http://www.jhechem.com/
Contact:+86-571-87396432
Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Doi:10.1016/S0957-4166(03)00483-X
(2003)Doi:10.1055/s-2006-944222
(2006)Doi:10.1023/A:1023931428206
(2003)Doi:10.1055/s-1976-24162
(1976)Doi:10.1021/ja00439a074
(1976)Doi:10.1021/jo00427a031
(1977)
