
Tetrahedron p. 9089 - 9094 (1993)
Update date:2022-08-03
Topics:
Baxter, Andrew J. G.
Teague, Simon
Heavy metal assisted halogen displacement on 2-halobenzoylpyrroles (2 and 3) leads to a simple synthesis of FPL 64176 (1) and a variety of analogues (4-10).The difluoro derivative (4), EC 50 1nM, and the amino linked analogue (7), EC 50 2.7nm, are present
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Doi:10.1055/s-1993-26037
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