Synthesis of optically active 4-benzyloxymethyl- and 4-(4-methoxyphenoxy)methylbuten-2-olides via lipase-mediated resolution

DOI: 10.1055/s-1993-26037

Source and publish data:

Synthesis p. 1253 - 1256 (1993)

Update date:2022-08-03

Topics:

Authors:

Takano Takano

Setoh Setoh

Yamada Yamada

Ogasawara

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Article abstract of DOI:10.1055/s-1993-26037

A new preparation of optically active 4-benzyloxymethyl- and 4-(4-methoxyphenoxy)methylbuten-2-olides has been developed by employing lipase-mediated resolution and palladium-mediated carbomethoxylation as key steps.

Full text of DOI:10.1055/s-1993-26037

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Product name:(+/-)-3-hydroxy-4-(4-methoxyphenoxy)-1-trimethylsilyl-1-butyne

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