Chemical and Pharmaceutical Bulletin p. 563 - 565 (2000)
Update date:2022-08-03
Topics:
Miyadera, Akihiko
Satoh, Koji
Imura, Akihiro
Two efficient and practical methods of synthesis of the C-10 substituent of DV-7751 (1), a novel quinolone carboxylic acid, were established. The first method utilizes an optical resolution of racemic 8-amino-6-benzyl-6- azaspiro[3.4]octane (13), while th
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