Journal of Fluorine Chemistry p. 13 - 14 (1994)
Update date:2022-08-04
Topics:
Burger, Klaus
Helmreich, Brigitte
Jendrewski, Oliver
A one-pot procedure for the synthesis of 2-fluoro-3-trifluoromethyl-substituted thiophens 6 from 1-aryl-4,4-difluoro-3-trifluoromethylbut-3-en-1-one (3) and phosphorus pentasulfide is described.The fluorine atom at C-2 of compounds 6 undergoes nucleophili
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Doi:10.1021/om00017a044
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