Tetrahedron p. 2029 - 2046 (1991)
Update date:2022-08-02
Topics:
Heuer, Monika
Hohgardt, Karsten
Heinemann, Frauke
Kuehne, Harald
Dietrich, Wolfgang
Grzelak, Detlef
Mueller, Dietrich
Welzel, Peter
Markus, Astrid
Van Heijenoort, Yveline
Van Heijenoort, Jean
Disaccharide derivative 1a is the smallest transglycosylase inhibiting compound known up to now. Structurally closely related compounds 11b and 19c have been synthesized. They do not inhibit the transglycosylase demonstrating the high specificity of the interaction between inhibitor 1a and the binding-site at the enzyme.
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