Journal of Medicinal Chemistry p. 2328 - 2333 (1994)
Update date:2022-08-02
Topics:
Hong, Seoung-Soo
Romstedt, Karl J.
Feller, Dennis R.
Hsu, Fu-Lian
Cupps, Thomas L.
et al.
The naphthalene analog of medetomidine (1), 4-<1-(1-naphthyl)ethyl>-1H-imidazole (2), is a highly potent, selective α2-adrenoceptor agonist.We have initiated a structure-activity relationship study of the replacement of the methyl group on the
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Doi:10.1016/S0040-4039(00)73254-0
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