Synthesis of (1R, cis)-3-aminomethyl-1,2,2-trimethylcyclopentane-methanol: Two approaches using α-camphidone

Article abstract of DOI:10.1016/S0040-4020(01)85077-8

(1R)-α-camphidone has proved to be extremely resistant to alkaline and acid hydrolysis, but the latter can be accomplished under drastic conditions. The aminoacid so obtained was transformed into the aminoalcohol 3, a desirable intermediate in the synthes