Synthesis of the C-1 sidechain of the squalestatins and zaragozic acid A

DOI: 10.1016/0040-4039(94)88298-3

Source and publish data:

Tetrahedron Letters p. 8263 - 8266 (1994)

Update date:2022-09-26

Topics:

Authors:

Parsons, Jack G.

Rizzacasa, Mark A.

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Article abstract of DOI:10.1016/0040-4039(94)88298-3

A synthesis of a protected C-1 side chain precursor (2) of the anti-cholesteremic agents the squalestatins and zaragozic acid A has been achieved in 9 steps from 1,4-butanediol. The key transformations involve a one pot oxidation/α-methylenation sequence

Full text of DOI:10.1016/0040-4039(94)88298-3

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