An efficient iminophosphorane-mediated synthesis for pyrido[3',2':4,5]thieno[3,2-d] pyrimidine derivatives

Article abstract of DOI:10.1016/S0040-4020(01)89699-X

A ready one-pot preparation for pyridothienopyrimidines bearing various substituents at position 2 of the pyrimidine ring is reported. The aza Wittig-type reaction of iminophosphoranes derived from the aldehyde 4 with heterocumulenes leads to functionaliz