Yb/TMS-Br promoted homocoupling reactions of aliphatic ketones and α,β-unsaturated ketones

DOI: 10.1016/S0040-4039(00)73126-1

Source and publish data:

Tetrahedron Letters p. 4111 - 4114 (1994)

Update date:2022-09-26

Topics:

Authors:

Taniguchi, Yuki

Nakahashi, Manabu

Kuno, Tatsuhiro

Tsuno, Masumi

Makioka, Yoshikazu

Takaki, Ken

Fujiwara, Yuzo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)73126-1

Ytterbium metal reacts with trimethylsilyl bromide (TMS-Br) to give divalent YbBr₂. YbBr₂ thus formed in situ, causes coupling reactions of aliphatic ketones and α,β-unsaturated ketones to give bissilylated 1,2-diols and 1,6-ketones, respectively, in good yields.

Full text of DOI:10.1016/S0040-4039(00)73126-1

Products guided by the article

Product name:1,1'-dimethyl-bicyclohexyl-3,3'-dione

Cas No:15840-91-2

R&D Labs maybe for 15840-91-2

Shanghai PotentPharm Science and Technology Co.,Ltd

Contact:86-021-51969655

Address:Unit B, Building 18, No.300, Chuantu Rd,Pudong District, Shanghai 201202, China
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.

Contact:15967177856

Address:Genglou Industrial Development Area
Zhangjiagang Jianing Import & Export Co.,Ltd.

Contact:086-512-55379012 13913607595

Address:NO.1 Guotai North Road Zhangjiagang Economic Development Zone,215600,Jiangsu,China
Jintan Jinnuo Chemical Co., Ltd.

Contact:+86-519-80199901

Address:Room 1804, Building 1, Huacheng Business Plaza, Jintan, Jiangsu, China
Xi'an Herbland Tech Inc.

Contact:+86-29-88710656

Address:South Tai bai Road, High Tech Development Zone, Xi'an China

Relevant to this article

Preparation and Application of Solid, Salt-Stabilized Zinc Amide Enolates with Enhanced Air and Moisture Stability

Doi:10.1002/anie.201700216
(2017)
Synthesis of substituted 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles and 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles by intramolecular nitrilimine cycloaddition

Doi:10.1016/j.tetlet.2014.02.068
(2014)
Asymmetric a-hydroxylation of a lactone with vinylogous pyridone by using a guanidine-urea bifunctional organocatalyst: Catalytic enantioselective synthesis of a key intermediate for (20S)-camptothecin analogues

Doi:10.1002/chem.201303633
(2014)
Design, synthesis and evaluation of 4-substituted anthra[2,1-c][1,2,5]thiadiazole-6,11-dione derivatives as novel non-camptothecin topoisomerase I inhibitors

Doi:10.1016/j.bmcl.2017.03.039
(2017)
An efficient synthesis of γ-amino β-ketoester by cross-Claisen condensation with α-amino acid derivatives

Doi:10.1016/S0040-4039(03)00464-7
(2003)
The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells

Doi:10.1016/j.tet.2017.11.029
(2018)

Article Doi