Journal of Organic Chemistry p. 6823 - 6827 (1994)
Update date:2022-08-04
Topics:
Jiang
Smallheer
Amaral-Ly
Wuonola
The total synthesis of the cytotoxic marine alkaloid, (±)-dragmacidin, trans-6,7-dibromo-3-[5-(6-bromo-1H-indol-3-yl)-4-methyl-2-piperazinyl] -1H-indol-4-ol, is described. The synthesis proceeds through the condensation of (6-bromoindol-3-yl)-α-(methylami
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