Tetrahedron Letters p. 4551 - 4554 (1994)
Update date:2022-08-03
Topics: Asymmetric synthesis Protection of Functional Groups Retrosynthetic analysis Purification and characterization Scale-up and optimization Solid-Phase Peptide Synthesis Cleavage and Deprotection
Ruiz, Maria
Ojea, Vicente
Shapiro, Gideon
Weber, Hans-Peter
Pombo-Willar, Esteban
The first enantiospecific synthesis of 2, a phosphonate isostere of phosphothreonine suitably protected for solid-phase peptide synthesis, has been achieved by coupling the highly face-selective conjugate addition of the lithium salt of Schoellkopf's bisl
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