Synthesis p. 2347 - 2352 (2008)
Update date:2022-08-03
Topics:
Tambade, Pawan J.
Patil, Yogesh P.
Bhanushali, Mayur J.
Bhanage, Bhalchandra M.
An efficient ligand-free protocol has been developed for the amincocarbonylation of aryl iodides with aromatic/aliphatic amines using palladium(II) acetate as a catalyst in water under milder operating conditions. The system tolerated a wide variety of hindered and functionalized aryl iodides/amines and afforded the desired amides in excellent yields at low catalyst concentration. Georg Thieme Verlag Stuttgart.
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