Substrate specificity of proline 4-hydroxylase: Chemical and enzymatic synthesis of 2S,3R,4S-epoxyproline

DOI: 10.1016/S0040-4039(00)60753-0

Source and publish data:

Tetrahedron Letters p. 4649 - 4652 (1994)

Update date:2022-08-05

Topics:

Authors:

Baldwin Baldwin

Field Field

Lawrence

Lee Lee

Robinson

Schofield

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Article abstract of DOI:10.1016/S0040-4039(00)60753-0

The substrate specificity of L-proline 4-hydroxylase, a 2-oxoglutarate dependent dioxygenase from Streptomyces griseoviridus P8648, was investigated. Preliminary assays measuring turnover of 2-oxyglutarate indicated 3,4-dehydro-L-proline was an efficient

Full text of DOI:10.1016/S0040-4039(00)60753-0

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