Novel thiazole-based heterocycles as selective inhibitors of fibrinogen- mediated platelet aggregation

DOI: 10.1021/jm00001a008

Source and publish data:

Journal of Medicinal Chemistry p. 34 - 41 (1995)

Update date:2022-08-05

Topics:

Authors:

Sanfilippo

Urbanski

Beers Beers

Eckardt Eckardt

Falotico

Ginsberg

Offord Offord

Press Press

Tighe Tighe

Tomko Tomko

Andrade-Gordon

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00001a008

The synthesis and biological activity of novel thiazole-based heterocycles as inhibitors of thrombin-induced human platelet aggregation are described. Further evaluation of selected compounds show they inhibit platelet aggregation as stimulated by a varie

Full text of DOI:10.1021/jm00001a008

Products guided by the article

Product name:1-(4-m-Tolyl-thiazol-2-yl)-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid ethyl ester

Cas No:159885-69-5

R&D Labs maybe for 159885-69-5

DU-HOPE INTERNATIONAL GROUP

Contact:+86-25-52346955

Address:199,JIANYE ROAD,NANJING,CHINA
LianYunGang Chiral Chemical(CHINA) CO.,LTD

Contact:+86-518-83616958 +86-519-82884848

Address:LianYunGang Chemical Industry Park (JiangSu)
zhenjiang runjing high purity chemical co ltd

Contact:+86-511-83361155

Address:No.8.haixi road,international chemical park
GIHI CHEMICALS CO.,LIMITED

Contact:+86-571-86217390

Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
Changzhou Litong Chemical Co., Ltd.

website:http://www.litonchem.com/

Contact:+86-519-86301238

Address:Laoba Rd, Hutang town Changzhou Jiangsu

Relevant to this article

Chemistry of the β-thiolactones: Substituent and solvent effects on thermal decomposition and comparison with the β-lactones

Doi:10.1021/jo500577c
(2014)
Br?nsted acid catalyzed azlactone ring opening by nucleophiles

Doi:10.1016/j.tet.2013.11.037
(2014)
Regioselective Synthesis of Prenylisoflavones. Syntheses of 2,3-Dehydrokievitone and Related Compounds

Doi:10.1246/cl.1994.2101
(1994)
A concise [C+NC+CC] coupling-enabled synthesis of kaitocephalin

Doi:10.1039/c4cc01692k
(2014)
An enantioselective synthesis of the C₂₄-C₄₀ fragment of (-)-pulvomycin

Doi:10.1039/c4cc01338g
(2014)
Synthesis, Molecular Structure, Fluxional Behavior, and Tricarbonyliron Transfer Reactions of (η⁴-1-Azabuta-1,3-diene)tricarbonyliron Complexes

Doi:10.1002/(SICI)1099-0682(199807)1998:7<993::AID-EJIC993>3.0.CO;2-6
(1998)

Article Doi