Novel thiazole-based heterocycles as selective inhibitors of fibrinogen- mediated platelet aggregation

DOI: 10.1021/jm00001a008

Source and publish data:

Journal of Medicinal Chemistry p. 34 - 41 (1995)

Update date:2022-08-05

Topics:

Authors:

Sanfilippo

Urbanski

Beers Beers

Eckardt Eckardt

Falotico

Ginsberg

Offord Offord

Press Press

Tighe Tighe

Tomko Tomko

Andrade-Gordon

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00001a008

The synthesis and biological activity of novel thiazole-based heterocycles as inhibitors of thrombin-induced human platelet aggregation are described. Further evaluation of selected compounds show they inhibit platelet aggregation as stimulated by a varie

Full text of DOI:10.1021/jm00001a008

Products guided by the article

Product name:1-(4-m-Tolyl-thiazol-2-yl)-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid ethyl ester

Cas No:159885-69-5

R&D Labs maybe for 159885-69-5

hangzhou sunchem trading co., ltd.

Contact:13588470430--

Address:Room 406-407, the 4th Building, No549
Hebei Think-Do Environment Co., Ltd

website:http://www.thinkdo-environment.com

Contact:0311-86510809-

Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Jinan Jianfeng Chemical Co., Ltd

Contact:0086-531-88110457

Address:sales01(-a-t-)pharmachemm{dot}c+o+m
Nanjing lanbai chemical Co.,Ltd.

Contact:+86-25-85499326

Address:Room 908, 9F Taiyue Building,No.285 Heyan Road
Suzhou Ryan Pharmachem Technology Co.,Ltd

Contact:+86-0512-68780025

Address:B-301,No.2 Taishan Road,Suzhou New District,Jiangsu,P.R. China

Relevant to this article

Chemistry of the β-thiolactones: Substituent and solvent effects on thermal decomposition and comparison with the β-lactones

Doi:10.1021/jo500577c
(2014)
Br?nsted acid catalyzed azlactone ring opening by nucleophiles

Doi:10.1016/j.tet.2013.11.037
(2014)
Regioselective Synthesis of Prenylisoflavones. Syntheses of 2,3-Dehydrokievitone and Related Compounds

Doi:10.1246/cl.1994.2101
(1994)
A concise [C+NC+CC] coupling-enabled synthesis of kaitocephalin

Doi:10.1039/c4cc01692k
(2014)
An enantioselective synthesis of the C₂₄-C₄₀ fragment of (-)-pulvomycin

Doi:10.1039/c4cc01338g
(2014)
Synthesis, Molecular Structure, Fluxional Behavior, and Tricarbonyliron Transfer Reactions of (η⁴-1-Azabuta-1,3-diene)tricarbonyliron Complexes

Doi:10.1002/(SICI)1099-0682(199807)1998:7<993::AID-EJIC993>3.0.CO;2-6
(1998)

Article Doi