Tetrahedron Letters p. 6877 - 6878 (1994)
Update date:2022-07-30
Topics:
Hedhli, Ahmed
Baklouti, Ahmed
Cambon, Aime
The synthesis of 3-F-alkyl-2-methoxy-3-phenylthiopropenals has been realised by basic hydrolysis of acetylated sulfides of the type R(F)-CH(OCH3)-CH(OAc)-S-Ph. A reaction suite is proposed to explain the formation of these aldehydes which may prove useful precursors in synthesis of F-alkylated heterocyclic compounds.
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