Beilstein Journal of Organic Chemistry p. 441 - 447 (2012)
Update date:2022-08-04
Al-Awadi, Nouria A.
Ibrahim, Maher R.
Elnagdi, Mohamed H.
John, Elizabeth
Ibrahim, Yehia A.
An efficient three component reaction with enaminones, primary amines and aldehydes resulted in easy access to 1,4-dihydropyridines with different substituents at the 1-, 3-, 4- and 5-positions. Microwaves improved the reaction yield, reducing also considerably the reaction time and the amount of solvent used. Chiral primary amines gave chiral 1-substituted-1,4-dihydropyridines. The 4-(1-naphthyl) and 4-(phenanthren-9-yl)dihydropyridine derivatives exhibited an interesting photoluminescence behavior, which suggests their potential application as suitable photoinduced intramolecular electron-transfer systems.
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