Synthetic Studies on Fully Substituted γ-Pyrone-Containing Natural Products: The First Total Synthesis of Onchitriol II

DOI: 10.1016/0040-4039(94)88516-8

Source and publish data:

Tetrahedron Letters p. 9581 - 9584 (1994)

Update date:2022-08-04

Topics: Synthetic studies Total synthesis Natural products Fully substituted Experimental terms

Authors:

Arimoto, Hirokazu

Nishiyama, Shigeru

Yamamura, Shosuke

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Article abstract of DOI:10.1016/0040-4039(94)88516-8

The first total synthesis of onchitriol II, a cytotoxic metabolite of mollusc Onchidium sp., is described.It employs mild cyclization method of triketides bearing optically active functional groups to the corresponding γ-py

Full text of DOI:10.1016/0040-4039(94)88516-8

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