
Tetrahedron Letters p. 9477 - 9480 (1994)
Update date:2022-08-04
Topics:
Paterson, Ian
Wallace, Debra J.
The fungal polyketide derivative (-)-ACRL toxin IIIB (4) has been prepared in 15 steps (21percent yield) from ketone (S)-7 with 88 percent overall ds.The boron-mediated anti aldol reaction of (S)-7 is used twice in the synthesis, controlling the stereoche
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