First Syntheses of Novel Paclitaxel(Taxol) Analogs Modified at the C4-Position

DOI: 10.1021/jo00100a011

Source and publish data:

Journal of Organic Chemistry p. 6156 - 6158 (1994)

Update date:2022-08-04

Topics:

Authors:

Chen, Shu-Hui

Kadow, John F.

Farina, Vittorio

Fairchild, Craig R.

Johnston, Kathy A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00100a011

A highly regiospecific method for the modification of paclitaxel at the C-4 position has been invented, as exemplified by the synthesis of the C-4 cyclopropyl ester of paclitaxel (4) and the C-4 benzoate of paclitaxel (5).

Full text of DOI:10.1021/jo00100a011

Products guided by the article

Product name:C₄₇H₇₄O₁₁Si₃

Cas No:160582-77-4

R&D Labs maybe for 160582-77-4

Daqing New Century Fine Chemical Co., Ltd.(expird)

Contact:010-57126694

Address:No.39, jinxing cun, honggang district
Puyang Huicheng Electronic Material Co., Ltd

website:http://huichengchem.weba.testwebsite.cn/index_en.html

Contact:+86-393-8910800

Address:West Section Shengli Road, Puyang457000, China
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China
Xinchang Yueding Chemical Co., Ltd.

Contact:86-571-56926323

Address:NO.90 BEIMENCHENGWAI CHENGGUAN TOWN XINCHANG
SHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.

website:http://www.tychemical.com

Contact:0086-358-3521713 3521715

Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China

Relevant to this article

Fe₃O₄@Sap/Cu(ii): An efficient magnetically recoverable green nanocatalyst for the preparation of acridine and quinazoline derivatives in aqueous media at room temperature

Doi:10.1039/d1ra01373d
(2021)
Bicyclic peptidomimetic tetrahydrofuro[3,2-b]pyrrol-3-one and hexahydrofuro[3,2-b]pyridine-3-one based scaffolds: Synthesis and cysteinyl proteinase inhibition

Doi:10.1016/j.bmc.2004.07.054
(2004)
Study into the cyclization of an epoxy-alcohol to the energetically disfavored product by peptides from non-biased combinatorial libraries

Doi:10.1016/S0040-4039(99)02196-6
(2000)
Heterocyclic steroids. XVI. A new synthesis of 13-aza-estrone.

Doi:10.1016/0040-4039(70)80091-0
(1970)
Dihydrodipyrrolo[b,e]phosphorins

Doi:10.1007/BF02252017
(1999)
Doi:10.1007/BF00910217
(1970)

Article Doi