Journal of Organic Chemistry p. 6156 - 6158 (1994)
Update date:2022-08-04
Topics:
Chen, Shu-Hui
Kadow, John F.
Farina, Vittorio
Fairchild, Craig R.
Johnston, Kathy A.
A highly regiospecific method for the modification of paclitaxel at the C-4 position has been invented, as exemplified by the synthesis of the C-4 cyclopropyl ester of paclitaxel (4) and the C-4 benzoate of paclitaxel (5).
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