Practical Syntheses of a Novel Tricyclic Dipeptide Mimetic Based on a -Azepino Indoline Nucleus: Application to Angiotensin-Converting Enzyme Inhibition

DOI: 10.1016/S0040-4039(00)78331-6

Source and publish data:

Tetrahedron Letters p. 7513 - 7516 (1994)

Update date:2022-08-03

Topics:

Authors:

De Lombaert, Stephane

Blanchard, Louis

Stamford, Lisa B.

Sperbeck, Donald M.

Grim, Michael D.

et al. et al.

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Article abstract of DOI:10.1016/S0040-4039(00)78331-6

Two stereocontrolled synthetic approaches towards 5-(S)-amino-1,2,4,5,6,7-hexahydro-azepino <3,2,1-hi> indole-4-one-2-(S)-carboxylic acid 1, based on intramolecular Friedel-Crafts acylations, are reported.This conformationally restricted tricyclic dipepti

Full text of DOI:10.1016/S0040-4039(00)78331-6

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