Synthesis of (2R,3R,4S)-2-hydroxymethylpyrrolidine-3,4-diol from (2S)-3,4-dehydroproline derivatives

DOI: 10.1016/0008-6215(94)84059-8

Source and publish data:

Carbohydrate Research p. 219 - 242 (1994)

Update date:2022-08-04

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Authors:

Goli, Deepa M.

Cheesman, Bruce V.

Hassan, Mohamed E.

Lodaya, Rita

Slama, James T.

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Article abstract of DOI:10.1016/0008-6215(94)84059-8

(2R,3R,4S)-2-Hydroxymethylpyrrolidine-3,4-diol (1,4-dideoxy-1,4-imino-D-ribitol) was synthesized in five steps from N-protected (2S)-3,4-dehydroproline methyl esters.The stereoselective reaction of osmium tetraoxide with dehydroproline derivatives gave hi

Full text of DOI:10.1016/0008-6215(94)84059-8

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