Amino acids and peptides. XXXVII. Synthesis of stereoisomeric nonapeptides corresponding to sequence 41-49 of eglin c and examination of their inhibitory activity against human leukocyte cathepsin G and α-chymotrypsin

DOI: 10.1248/cpb.42.1518

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1518 - 1521 (1994)

Update date:2022-08-04

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Authors:

Fujii Fujii

Tsuboi Tsuboi

Asada Asada

Nagamatsu

Yamamoto

Okada Okada

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Article abstract of DOI:10.1248/cpb.42.1518

A nonapeptide, H-Ser-Pro-Val-Thr-Leu-Asp-Leu-Arg-Tyr-OH, corresponding to sequence 41-49 of eglin c inhibited leukocyte cathepsin G and α-chymotrypsin with K(i) values of 2.2 x 10^-5 and 7.2 x 10^-6 M, respectively, although eglin c it

Full text of DOI:10.1248/cpb.42.1518

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